The Quality Of A Neuromuscular Blockade Discussion
Order 5994039
The Quality Of A Neuromuscular Blockade Discussion
1. 21. Which statement regarding the phase II block can be associated with
succinylcholine administration is true?
A. Phase II block occurs only after prolonged exposure to succinylcholine.
B. Receptor desensitization is a mechanism responsible for phase II block.
C. Inhalation anesthetics delay the onset of phase II block.
D. Phase II block results in train-of-four (TOF) fade but not tetanic fade.
2. A patient was maintained on a succinylcholine infusion for 8 hours during
surgery and does not regain spontaneous ventilation 30 minutes after the
infusion was discontinued. TOF yields 1 twitch. Which of the following is the
best course of action?
A. Give neostigmine.
B. Send pseudocholinesterase activity test.
C. Give naloxone.
D. Wait for spontaneous recovery.
3. Which mechanism best explains the fasciculations often seen preceding a phase
I block by succinylcholine?
A. Activation of presynaptic nAchR
B. Activation of postsynaptic nAchR
C. Prolonged muscle depolarization
D. Prolonged muscle repolarization
4. A patient on succinylcholine infusion has a TOF ratio of 0.3. What does this tell
about the patient’s degree of paralysis?
A. Patient is in phase I block.
B. Patient is in phase II block.
C. Patient is recovering from block.
D. Cannot tell from given information.
The Quality Of A Neuromuscular Blockade Discussion
5. Monitoring the TOF to assess the quality of a neuromuscular blockade offers
what advantage over single twitch monitoring?
A. TOF offers objective assessment of fade.
B. TOF ratio correlates with the amount of stimulating current applied.
C. TOF does not require baseline measurement.
D. TOF is best at detecting the onset of neuromuscular blockade.
6. When the TOF ratio is 0.7, what portion of the AchRs is still blocked?
A. 25%
B. 50%
C. 75%
D. 95%
7. A TOF yields 0 twitch. Repeated 1 Hz stimulation following a 5-second 50 Hz
tetanus produces 1 twitch. Assuming the patient was given an intermediateacting NMB, how much time is expected until recovery to TOF twitch count of
1?
A. 1-2 minutes
B. 5-10 minutes
C. 20-30 minutes
D. >1 hour
8. 28. Compared with TOF, what is an advantage of double-burst stimulation
(DBS) for monitoring of neuromuscular blockade?
A. Easier to detect fade
B. Does not use tetanic stimuli
C. Ability to immediately apply a repeat stimulus
D. Smaller current
9. Side effects of neostigmine include all of the following EXCEPT which one?
A. Salivation
B. Tachycardia
C. Nausea/vomiting
D. Bowel motility
10. How long would a patient with a dibucaine number of 20 be expected to remain
paralyzed after an intubating dose of succinylcholine?
A. 4 minutes
B. 40 minutes
C. 4 hours
D. 4 days
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