The Inheritance Pattern Of Duchenne Muscular Dystrophy

The Inheritance Pattern Of Duchenne Muscular Dystrophy
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The Inheritance Pattern Of Duchenne Muscular Dystrophy
1. What differentiates Lambert-Eaton myasthenic syndrome (LEMS) from
myasthenia gravis?
A. Patients with LEMS often have autonomic dysfunction.
B. LEMS results from autoantibodies to the postsynaptic AchRs.
C. Patients with LEMS feel more proximal than distal weakness.
D. Patients with LEMS get progressively fatigued with repetitive use of muscles.
2. In patients with myasthenia gravis, which factor best predicts the risk of
requiring prolonged intubation and mechanical ventilator support?
A. Age of illness onset
B. Involvement of muscle groups
C. Dosage of acetylcholinesterase inhibitor at home
D. Circulating autoantibody level
3. How do patients with myasthenia gravis react to depolarizing NMBs and
nondepolarizing NMBs?
A. Sensitive to depolarizing, but insensitive to nondepolarizing NMBs
B. Insensitive to depolarizing, but sensitive to nondepolarizing NMBs
C. Sensitive to both depolarizing and nondepolarizing NMBs
D. Insensitive to both depolarizing and nondepolarizing NMBs
4. A patient with myasthenia gravis presents with muscle weakness and
respiratory failure. What is the best way to differentiate a myasthenia crisis
from a cholinergic crisis?
A. Presence or absence of GI symptoms
B. Pupillary exam
C. Tensilon test
D. Excessive sweating
5. What is the inheritance pattern of Duchenne muscular dystrophy (DMD)?
A. Autosomal dominant
B. Autosomal recessive
C. X-linked dominant
D. X-linked recessive
The Inheritance Pattern Of Duchenne Muscular Dystrophy
6. 36. For patients with myotonic dystrophy, prolonged muscle contraction
(myotonia) can be triggered by exposure to all of the following agents EXCEPT
which one?
A. Succinylcholine
B. Rocuronium
C. Potassium
D. Neostigmine
7. Which intravenous anesthetic agent should be avoided in patients with
mitochondrial myopathy?
A. Propofol
B. Etomidate
C. Ketamine
D. Dexmedetomidine
8. Malignant hyperthermia is a known risk for patients with the following
conditions EXCEPT which one?
A. King Denborough syndrome
B. Multiminicore disease
C. Central core disease
D. Central cord syndrome
9. Which intravenous fluid should be avoided in patients with mitochondrial
disorder?
A. Normal saline
B. Lactated Ringer (LR)
C. Dextrose
D. Albumin
10. Psuedocholinesterase activity is increased in which of the following conditions?
A. Pregnancy
B. Liver failure
C. Obesity
D. Malignancy
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