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1. Which one of the following is NOT a
component of the blood-brain barrier?
a. Capillary endothelial cells
b. Astrocytic foot processes
c. Basement membrane
d. Tight junctions
e. Microglia
2. Which one of the following regions has an
intact blood-brain barrier?
a. Subforniceal organ
b. Area postrema
c. Median eminence
d. Posterior pituitary
e. Pineal gland
f. Subcommissural organ
g. Organum vasculosum of lamina
terminalis
3. Which one of the following statements
regarding the area postrema is LEAST
accurate?
a. It is located in the dorsomedial medulla in
the caudal part of the fourth ventricle
b. Its blood supply is mostly from the anterior inferior cerebellar artery
c. It is a circumventricular organ
d. It plays a role as a chemoreceptor
trigger zone
e. It expresses 5-HT3 receptors
4. Which one of the following statements
regarding the production of CSF by choroid
plexus cells is LEAST accurate?
a. Requires ultrafiltration of plasma to form
extracellular fluid at basolateral
membrane
Order Neurophysiology Discussion Assignment Help
b. Formation is primarily generated by net
secretion of Na
, Cl, and HCO3
into
ventricles
c. Water is actively pumped into the ventricles via Aquaporin 1 channels in the apical
membrane
d. Active transport of Na into the ventricles
via Na
/K ATPase occurs at the basolateral membrane
e. Basolateral membrane Na influx via
Na
/H exchange and Na
/HCO3
cotransport channels.
5. Which one of the following statements
regarding axonal transport is LEAST
accurate?
a. Large membranous organelles are transported by fast kinesin dependent anterograde transport and dynein dependent
retrograde transport
b. Cytosolic proteins are transported by fast
transport
c. Occurs by retrograde transport
d. Anterograde transport is dependent upon
microtubules and the ATPase kinesin
e. Rabies virus spreads by retrograde axonal
transport
6. Which one of the following statements
regarding the concentration of ions in extracellular and intracellular compartments is
LEAST accurate?
a. Extracellular sodium ion concentration is
approximately 140 mM (140 mEq/l)
b. Intracellular potassium ion concentration
is approximately 160 mmol/l (160 mEq/L)
c. Extracellular chloride ion concentration is
approximately 110 mM (110 mEq/l)
d. Intracellular calcium ion concentration is
approximately 2 mM (4 mEq/l)
e. Extracellular bicarbonate ion concentration is approximately 22-26 mmol/l
7. Which one of the following statements concerning the resting membrane potential is
most accurate?
a. Maintenance of the resting membrane
potential is an energy dependent process
requiring Na/K-ATPase
b. A membrane is depolarized when there is
an increase in separation of the charge
across it from baseline
c. Neurons become depolarized when the
charge inside the cell becomes more negative compared to its resting sta
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