Order Cholinergic Drugs Discussion Solutions

Order Cholinergic Drugs Discussion Solutions
Order 5978982
Order Cholinergic Drugs Discussion Solutions
Directions for questions 1−5
Match each cholinergic drug w ith the appropriate description
(each lettered option can be selected once, m ore than once, or
not at all).
A. Acetylcholine
B. Bethanechol
C. Carbachol
D. Donepezil
E. Edrophonium
F. Muscarine
G. Neostigm ine
H. Parathion
I. Pilocarpine
J. Pralidoxim e
K. Physostigm ine
Di culty level: Easy
1. Inhibition of cholinesterases by this drug is very short (2−10
minutes).
Di culty level: Easy
Order Cholinergic Drugs Discussion Solutions
2. This drug can inhibit cholinesterases equally well in the periphery as in the central nervous system .
Di culty level: Easy
3. This com pound can be absorbed e ectively through the intact
skin.
Di culty level: Easy
4. This drug is able to regenerate cholinesterases blocked by
organophosphates.
Di culty level: Easy
5. This drug can inhibit cholinesterases and directly activate
Nm cholinergic receptors.
Di culty level: Medium
6. A new autonom ic drug was given intravenously to dogs
during a lab experim ent. It was found that the drug was able
to increase cholinergic transm ission in both the peripheral
and central nervous system s. Which of the follow ing drugs
does the new agent m ost resem ble?
A. Acetylcholine
B. Carbachol
C. Bethanechol
D. Neostigm ine
E. Physostigm ine
Di culty level: Hard
7. A 62-year-old m an su ering from open-angle glaucom a underwent ocular surgery for canaloplast y. Before the operation, the ophthalm ologist instilled a few drops of carbachol in
the conjunctival sac. Which of the follow ing anatom ical structures represents the prim ary site of action of the drug in this
patient?
A. Ganglionic neurons
B. Ciliary m uscle
C. Lens
D. Radial m uscle of the iris
E. Brainstem
Di culty level: Hard
8. A 51-year-old diabetic wom an presented to the em ergency
room w ith severe ocular pain and redness, decreased vision,
colored halos, and nausea and vom iting. Ophthalm oscopy revealed anterior cham ber in am m ation, and tonom etry m easured an intraocular pressure of 48 m m Hg in the right eye
(norm al 10−20 m m Hg). A diagnosis of an acute glaucom a attack was m ade, and two drugs were instilled in the conjunctival sac. Another drug was given by the sam e route 15 m inutes
later. W hich of the follow ing three drugs were m ost likely
administered?
A. Tim olol, apraclonidine, and pilocarpine
B. Hom atropine, carbachol, and tim olol
C. Scopolam ine, dorzolam ide, and phenylephrine
D. Hom atropine, carbachol, and dorzolam ide
E. Prazosin, physostigm ine, and m annitol
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