Drugs for Depressive and Anxiety Disorders

Drugs for Depressive and Anxiety Disorders
Order 5993721
Drugs for Depressive and Anxiety Disorders
Directions for questions 1−5
Match each drug w ith the appropriate description (each lettered
option can be selected once, m ore than once, or not at all).
A. Am itriptyline
B. Bupropion
C. Citalopram
D. Fluoxetine
E. Mirtazapine
F. Phenelzine
G. Selegiline
H. Trazodone
I. Venlafaxine
Di culty level: Easy
1. A drug w ith pronounced anticholinergic properties
Di culty level: Easy
2. A nonselective m onoam ine oxidase inhibitor
Di culty level: Easy
3. An active m etabolite of this drug has a half-life of about 10
days.
Di culty level: Easy
4. This drug can prolong the electrocardiogram QT interval.
Di culty level: Easy
5. A serotonin 5-HT2A presynaptic receptor blocker
Di culty level: Medium
6. A 43-year-old m an recently diagnosed w ith m ajor depressive
disorder started a pharm acotherapy with an antidepressant
drug. Which of the follow ing is m ost likely the com m on m echanism underlying the therapeutic e ectiveness of long-term
therapy w ith m ost antidepressants drugs?
Drugs for Depressive and Anxiety Disorders
A. Inhibition of central m onoam ine m etabolism
B. Upregulation of central postsynaptic adrenoceptors
C. Increased expression of brain-derived neurotrophic factor
D. Decreased hippocam pal neurogenesis
E. Increased glutam atergic transm ission
Di culty level: Medium
7. A 55-year-old m an su ering from severe depression was
brought to the em ergency departm ent after an overdose of
an unknow n m edication. Physical exam ination showed a lethargic patient w ith dilated pupils. Vital signs were blood pressure 95/55 m m Hg, heart rate 130 bpm , respirations 10/m in.
An electrocardiogram (ECG) showed tachycardia w ith w ide
QRS com plex. Which of the follow ing drugs m ost likely caused
the patient’s signs and sym ptom s?
A. Sertraline
B. Lithium
C. Bupropion
D. Phenelzine
E. Am itriptyline
F. Clonazepam
Di culty level: Medium
8. A 45-year-old wom an com plained of dizziness to the point of
fainting upon standing. She also felt drowsy for m ost of the
day. The patient had been adm itted to a hospital psychiatric
unit 2 weeks earlier because of her third episode of m ajor depressive disorder. She had been receiving an antidepressant
therapy for the past 10 days. Which of the follow ing drugs
m ost likely caused the patient’s sym ptom s?
A. Bupropion
B. Mirtazapine
C. Am itriptyline
D. Paroxetine
E. Venlafaxine
F. Lithium
Di culty level: Medium
9. A 48-year-old m an recently diagnosed w ith generalized anxiety disorder started an appropriate therapy w ith a drug that
acts by increasing the availabilit y of both norepinephrine
and serotonin in the synaptic cleft of central nervous system
neurons. W hich of the follow ing drugs was m ost likely
prescribed?
A. Am itriptyline
B. Citalopram
C. Venlafaxine
D. Lorazepam
E. Bupropion
F. Trazodone
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