Drugs Affecting the Autonomic Nervous System Discussion

Drugs Affecting the Autonomic Nervous System Discussion
Order 5908890
Drugs Affecting the Autonomic Nervous System Discussion
1. Postoperative urinary retention may be best treated
with
A. DFP
B. carbachol
C. ephedrine
D. bethanechol
E. atropine
2. When it is desired to restrict neostigmine’s effect to
skeletal muscle, its visceral actions may be blocked by
A. pilocarpine
B. d-tubocurarine
C. physostigmine
D. atropine
E. chlorisondamine
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30 / Pharmacology
Drugs Affecting the Autonomic Nervous System Discussion
3. Nicotinic receptors in autonomic ganglia are blocked by
which of the following?
A. Eucatropine
B. Trimethaphan
C. Carbachol
D. Edrophonium
E. Hemicholinium
76. Which of the following effects is produced by stimula¬
tion of adrenergic nerves?
A. Contracts the detrusor muscle of the urinary bladder
B. Contracts the sphincter muscle of the gastrointesti¬
nal tract
C. Relaxes the smooth muscle of the vasa deferentia
D. Contracts the bronchial smooth muscle
E. Relaxes the radial muscle of the iris
77. The enhanced pressor response to norepinephrine in
man after the administration of amitriptyline is most
likely caused by
A. increased sensitivity of tissue to norepinephrine
B. increased activity of catechol-O-methyltransferase
(COMT)
C. interference with uptake of norepinephrine into
adrenergic nerves
D. increased activity of monoamine oxidase
E. decreased destruction of norepinephrine by meta¬
bolic enzymes
78. The major pathway for the removal of norepinephrine
released from nerves into the synaptic gap is
A. degradation by monoamine oxidase
B. uptake into adrenergic nerve
C. diffusion from the synapse into general circulation
D. binding with plasma proteins
E. uptake into smooth muscle cells of spleen, heart,
and kidney
Autonomic Nervous System / 31
Drugs Affecting the Autonomic Nervous System Discussion
79. Atropine is probably effective as an antiparkinsonian
agent because it
A. enhances the physiologic effects of dopamine
centrally
B. enhances the entrance of the precursors (e.g., tyro¬
sine) of dopamine through the blood-brain barrier
C. inhibits the actions of acetylcholine, which is a
physiologic antagonist to dopamine in the striatum
D. inhibits the actions of serotonin by reducing forma¬
tion in brain tissue
E. stimulates dopaminergic receptors
80. One diagnostic procedure for pheochromocytoma relies
on the antiadrenergic activity of
A. guanethidine
B. phentolamine
C. alpha-methyldopa
D. pargyline
E. cocaine
81. Which of the following is an accepted therapeutic use of
epinephrine?
A. Combinations with local anesthetics in 1:1000 con¬
centrations
B. Treatment of pheochromocytoma
C. IV infusion in cases of hemorrhagic shock
D. Treatment of cardiac asthma
E. Treatment of acute hypersensitivity reaction to
drugs
82. Pralidoxime 2-PAM is capable of preventing the actions
of
A. MAO inhibitors
B. organophosphorus anticholinesterases
C. acetylcholine
D. histamine
E. serotonin
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