Discus Optical Properties of Biomolecules 2.1 In a sample cell of path length l=1 cm a compound of unknown concentration is measured. For light of λ=550 nm the intensity after the sample is reduced to 80% of the original light intensity before the sample cell, I0. Assume that this reduction in light intensity is due solely to absorption by the compound of unknown concentration. What […]

Order Basic Fluorescence Techniques Assignment 3.1 Fluorescent labels are designed in such a way that the fluorescent quantum yield is as high as possible and that the fraction of triplet state remains as small as possible upon excitation. Some time constants of two different fluorescent labels are given below: Label A Label B Radiative S1 ® S0 transition (fluorescence): τFl = 5 ns τFl = […]

Order Magnetic Resonance Techniques Assignment 5.1 Explain why higher magnetic field strengths result in a better resolution of magnetic resonance spectrometers. 5.2 Discuss the advantages of pulsed NMR methods over NMR methods in which the absorption of continuous radiowaves is measured. 5.3 Figure 5.4 illustrates the reasons for the splitting and the intensities of the signals for the methyl group protons of ethanol (shown in […]

Order Mass Spectrometry Assignment 6.1 Modern mass spectrometers allow us to combine electrospray ionization with a time-of-flight analyser. Discuss the potential advantages of such an arrangement. 6.2 a. In a MALDI-TOF experiment ions are detected 250 μs after laser irradiation. What is the mass of one mole of the investigated molecules Figure 6.14 Peptide ladder sequencing. The differences between the mass peaks correspond to the […]

Order Fluorescence Microscopy Discussion 7.1 In the inset of Figure 7.1 the characteristic dimensions of a confocal detection volume are defined by the axial and lateral resolution, z0 and r0, respectively. What are the most important factors that determine the magnitude of these two parameters? 7.2 What is the diffraction-limited resolution of a microscope objective with a numerical aperture of 1.2 when using light of […]

Order Value stream map Assignment ◾ What parts of our processes add value from our patient’s and staff’s perspectives? ◾ What parts of our processes add cost? ◾ What parts of our processes are unreliable and create variation? ◾ What parts of our processes limit our capacity? ◾ What parts of our processes reduce our flexibility? ◾ What parts of our processes do we need […]

Order Sustaining Lean in Healthcare Assignment 1. Process analysis and observation 2. Identifying opportunities for improvement 3. Testing improvement opportunities by using the improvement model 4. Determining best solutions and developing a management plan to implement, sustain and, if appropriate, spread 5. Presenting final recommendations to champion and other leaders, as needed for approval prior to implementation (typically the last day of the event) Order […]

Order Crime and Criminology Assignment 1. What is “criminology”? How does criminology relate to other social science disciplines? 2. What is a scientific theory? How can you tell whether or not a theory is good? 3. What is the substantive criminal law? Describe the two main perspectives on the criminal law, and give an example of a crime that is consistent with each perspective. 4. […]

Order Sources of Crime Statistics Assignment Define the elements of the Uniform Crime Report (UCR) and identify its strengths and weaknesses as a crime data source. Pg. 29 Define the elements of the National Crime Victimization Survey (NCVS) and identify its strengths and weaknesses as a crime data source. Pg. 33 Define the elements of the National Incident-Based Reporting System. Pg. 32 Understand what patterns […]

Order Criminology and Academics Assignment Define criminology and understand how this field of study relates to other social science disciplines. Pg. 4 Understand the meaning of scientific theory and its relationship to research and policy. Pg. 8 Recognize a “good” theory of crime, based on criteria such as empirical support, scope, and parsimony. Pg. 10 Know the criteria for establishing causation and identify the attributes […]