Order Molecular Assays of NS Tumors

Order Molecular Assays of NS Tumors
Order 5953820
Order Molecular Assays of NS Tumors
1. Molecular assays of NS tumors:
a. B-cell and T-cell receptor gene rearrangement
b. BRAF-KIAA1549 gene fusion/
duplication
c. Chromosome 1p/19q loss
d. EGFR gene amplification/10q loss
e. EWSR1 gene rearrangement
f. MGMT promotor methylation status
g. Monosomy chromosome 6
h. MYC gene amplification
i. SMARCB1 gene loss/INI1 protein absent
j. Wnt signaling pathway upregulation
For each of the following descriptions, select the
most appropriate answers from the list above.
Each answer may be used once, more than once
or not at all.
1. Diagnosis of atypical teratoid/rhabdoid
tumor
2. Response to alkylating agents in high grade
glioma
3. Found in most pilocytic astrocytomas
Order Molecular Assays of NS Tumors
2. Tumor syndromes:
a. APC
b. MEN1
c. NF-1
d. NF-2
e. PTCH
f. PTEN
g. SMARCB1
h. TP53
i. TSC1/TSC2
j. VHL
For each of the following descriptions, select the
most appropriate answers from the list above.
Each answer may be used once, more than once
or not at all.
1. Gliomas and medulloblastoma
2. AT/RT
3. Hemangioblastoma
26. Tumor markers:
a. Alpha-fetoprotein (AFP)
b. Beta-2-microglobulin
c. Beta-human chorionic gonadotropin
d. CA-125
e. CA15-3/CA27.29
f. CA19-9
g. Calcitonin
h. CEA
i. Chromogranin-A
j. Cytokeratin fragment 21-1
k. HE-4
l. LDH
m. PSA
For each of the following descriptions, select the
most appropriate answers from the list above.
Each answer may be used once, more than once
or not at all.
1. Neuroendocrine tumors
2. Multiple myeloma
3. Liver and germ cell cancers
3. Cytopathology of neurones and glia:
a. Central chromatolysis
b. Cowdry type A intranuclear inclusions
c. Flexner Wintersteiner rosette
d. Hirano Bodies
e. Homer-Wright rosette
f. Inclusion bodies
g. Lewy bodies
h. Negri bodies
i. Neurofibrillary tangles
j. Perivascular pseudorosette
k. Pick Bodies
l. Pick Cells
m. Schiller-Duval bodies
n. Verocay bodies
For each of the following descriptions, select the
most appropriate answers from the list above.
Each answer may be used once, more than once
or not at all.
1. Schwannoma
2. Ependymoma
3. Retinoblastoma
4. Rabies virus
5. Alzheimer’s disease
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