Order GI and Hepatic Systems Essay
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Order GI and Hepatic Systems Essay
1. What percentage of hepatic blood flow comes from the portal vein?
A. 25%
B. 50%
C. 75%
D. 90%
2. What percentage of oxygen delivery to the liver comes from the hepatic
artery?
A. 25%
B. 50%
C. 75%
D. 90%
3. Hepatomegaly may be observed in all of the following conditions EXCEPT
which one?
A. Congestive heart failure
B. Hypovolemic shock
C. Leukemia
D. Renal failure
4. The round ligament separates which 2 hepatic segments?
A. 1 and 2
B. 2 and 3
C. 3 and 4
D. 4 and 5
5. Which of the following signaling factors is decreased in a cirrhotic liver?
A. Nitric oxide
B. Endothelin
C. Norepinephrine
D. Thromboxane A2
Order GI and Hepatic Systems Essay
6. 6. Compared with the hepatic artery, which statement about portal vein is true?
A. Portal vein supplies 50% of the liver’s overall blood flow.
B. Portal vein is a low-pressure/low-resistance system.
C. Portal vein blood is richly oxygenated.
D. Portal vein supplies 75% of the liver’s overall oxygen delivery.
7. Increase in the serum level of which of the following may be observed in liver
failure?
A. IgG
B. Factor VII
C. Albumin
D. Ammonia
8. Glucose is synthesized in the liver as the result of all of the following processes
EXCEPT which one?
A. Glycogenolysis
B. Gluconeogenesis
C. Tricarboxylic acid cycle
D. Oxidation of lactate
9. In the assessment of patient with liver failure, which parameter is used in the
MELD (model for end-stage liver disease) scoring system but NOT the ChildPugh scoring system?
A. Creatinine
B. International normalized ratio (INR)
C. Bilirubin
D. Albumin
10. Elevation in the serum level of which factor is a specific marker of acute liver
injury?
A. Aspartate aminotransferase (AST)
B. Alanine aminotransferase (ALT)
C. Alkaline phosphatase
D. Lactate dehydrogenase (LDH)
11. Which laboratory test is a sensitive indicator for decreased synthetic function
of the liver?
A. Aspartate aminotransferase
B. Albumin
C. International normalized ratio
D. γ-Glutamyl transpeptidase (GGT)
12. A liver failure patient may show all of the following clinical signs EXCEPT
which one?
A. Jaundice
B. Easy bruising
C. Confusion
D. Hyperglycemia
13. The level of which coagulation factor may not be affected by advanced liver
disease?
A. II
B. V
C. VII
D. VIII
14. 14. A patient with an elevated total serum bilirubin and an elevated indirect
serum bilirubin may have which of the following conditions?
A. Gilbert syndrome
B. Primary biliary cirrhosis
C. Primary sclerosing cholangitis
D. Wilson disease
Order GI and Hepatic Systems Essay
15. Which of the following is the mechanism by which lactulose relieves symptoms
of hepatic encephalopathy?
A. Inhibition of hepatic ammonia production
B. Increasing the conversion of ammonia to urea
C. Acidification of the colon
D. Diuresis to decrease intracranial pressure
16. Metabolism and clearance of morphine may be increased in which of the
following situations?
A. Congestive heart failure
B. Inhaled anesthetics
C. Intra-abdominal surgery
D. Sepsis
17. The clearance of which of the following drugs through the liver is NOT
dependent on liver blood flow?
A. Propofol
B. Morphine
C. Fentanyl
D. Midazolam
18. Inducers of cytochrome P450 system include all of the following EXCEPT
which one?
A. Ethanol
B. Phenytoin
C. Isoniazid
D. Rifampin
19. A 60-year-old man who has just been listed for a liver transplant remains
overly sedated for 24 hours after being administered midazolam 4 mg IV. What
other medication might he be taking at the same time?
A. Erythromycin
B. Penicillin
C. Gentamicin
D. Vancomycin
20. A patient with deactivating mutation in the cytochrome P450 2D6 gene may
have ineffective analgesia from which of the following opioids?
A. Morphine
B. Codeine
C. Fentanyl
D. Methadone
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