Order Adverse Effects of Drugs Discussion

Order Adverse Effects of Drugs Discussion
Order 5990322
Order Adverse Effects of Drugs Discussion
1. A 23-year-old wom an com plained to her physician that the
diphenhydram ine she used to prevent m otion sickness w hen
traveling by boat was e ective in preventing vom iting but
caused drowsiness and dry m outh. Which of the follow ing
term s best explains the underlying cause of these drug-related
adverse e ects?
A. Genetic predisposition
B. Nonspeci c cytotoxicity
C. Drug−receptor interaction
D. Im m unologic response
E. Preexisting pathology
Di culty level: Medium
2. Five new anticonvulsant drugs (P, Q, R, S, and T) were tested in
laboratory anim als. It was found that all of the drugs had approxim ately the sam e lethal dose that produces death in 50%
of subjects (LD50). The m edian e ective dose of each drug is
reported below:
Order Adverse Effects of Drugs Discussion
3. A 51-year-old m an reported to his physician that in the m orning he noticed his urine was cloudy and red. The m an had
been taking an oral anticoagulant for 3 weeks to treat a deep
venous throm bosis. If the patient’s sym ptom s were caused by
the anticoagulant, w hich of the follow ing adverse drug reactions was m ost likely involved?
A. Overdose toxicit y
B. Autoim m une reaction
C. Idiosyncratic reaction
D. Pseudoallergic reaction
E. Im m ediate allergic reaction
Di culty level: Hard
4. A 23-year-old wom an scheduled for surgical dilation and curettage was anesthetized w ith thiopental. Shortly after recovery from the anesthesia, the wom an had generalized seizures
followed by a deep com a. Further inform ation given by her
husband indicated that the patient’s m other had su ered from
acute interm ittent porphyria. If the com a was caused by thiopental, w hich of the follow ing drug reactions was m ost likely
involved?
A. Type II allergic reaction
B. Delayed allergic reaction
C. Idiosyncratic reaction
D. Pseudoallergic reaction
E. Overdose toxicit y
Di culty level: Medium
5. A 28-year-old wom an w ho had had a m itral valve replacem ent for rheum atic heart disease 2 years ago had her suspected pregnancy con rm ed by a positive pregnancy test. Her
current m edications include the anticoagulant warfarin (U.S.
Food and Drug Adm inistration [FDA] category for teratogenic
risk D) and am oxicillin (FDA category B). Which of the following would be the best course of action to be im plem ented by
her fam ily physician?
A. Stop all m edications throughout pregnancy
B. Suspend warfarin for the rst trim ester of pregnancy
C. Replace warfarin w ith heparin and continue am oxicillin
D. Continue warfarin and replace am oxicillin w ith penicillin G
E. Reduce the dose of warfarin and continue am oxicillin
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