Order Drugs for Bipolar Disorders Assignment

Order Drugs for Bipolar Disorders Assignment
Order 5902934
Order Drugs for Bipolar Disorders Assignment
Directions for questions 1−4
Match each drug used in bipolar disorder w ith the appropriate
description (each lettered option can be selected once, m ore than
once, or not at all).
A. Aripiprazole
B. Carbam azepine
C. Lam otrigine
D. Lithium
E. Quetiapine
F. Risperidone
G. Valproic acid
Di culty level: Easy
1. A dopam inergic receptor partial agonist e ective in bipolar
disorders
Di culty level: Easy
2. This drug can increase the risk of spina bi da in the new born
w hen given during pregnancy.
Di culty level: Easy
3. This drug is e ective for the treatm ent of both acute m ania
and all t ypes of epilepsy.
Di culty level: Easy
Order Drugs for Bipolar Disorders Assignment
4. The hepatic clearance of this drug is zero.
Di culty level: Medium
5. A 45-year-old m an w ith a long history of bipolar disorder had
been stable on a m aintenance lithium treatm ent for the past
year. W hich of the follow ing best describes a current working hypothesis about the m olecular m echanism of action of
lithium ?
A. Increased synthesis of adenylyl cyclase
B. Increased synthesis of inositol m onophosphatase
C. Increased serotonin reuptake into serotonergic term inals
D. Upregulated β-adrenoceptors
E. Decreased synthesis of inositol triphosphate (IP3) and diacylglycerol (DAG)
F. Increased glutam atergic activity
Di culty level: Medium
6. A 68-year-old m an was adm itted to a psychiatric hospital because of depression, hopelessness about his condition, sleep
disturbances, and poor appetite. He had a long history of previous hospitalizations for m anic or depressive episodes and
had experienced ve m ood sw ings in the past year, including episodes of depression and hypom ania. Despite adequate
plasm a levels, he had not responded to lithium . Which of the
follow ing drugs would be appropriate for the patient at this
tim e?
A. Haloperidol
B. Bupropion
C. Fluphenazine
D. Quetiapine
E. Diazepam
F. Am itriptyline
Di culty level: Easy
7. A 34-year-old m an was adm itted to a psychiatric hospital
during an acute m anic attack. The m an had his rst m anic
attack at the age of 27 and had had three other m anic attacks
since then. A diagnosis of acute m ania was m ade, and a therapy was prescribed that included a drug that acts by blocking
D2 and 5-HT2 receptors in the brain. Which of the follow ing
drugs was m ost likely prescribed?
A. Lam otrigine
B. Clom ipram ine
C. Valproic acid
D. Olanzapine
E. Lithium
F. Trazodone
Di culty level: Medium
Order Drugs for Bipolar Disorders Assignment
8. A 36-year-old wom an com plained to her physician that she
felt tired, su ered from constipation, and had gained weight
in recent weeks. She also com plained of feeling cold and of
absence of m enses during the last 3 m onths. The wom an had
been su ering from a bipolar disorder and had been m aintained successfully on lithium therapy for 1 year. In addition
to lithium , her present m edication included cim etidine for duodenal ulcer and loratadine for hay fever. Which of the following was the m ost likely cause of the patient’s sym ptom s?
A. Lithium -induced hypothyroidism
B. Cim etidine-induced decrease in lithium m etabolism
C. Adverse e ects of cim etidine
D. Central depressant e ects of loratadine
E. Worsening of the disease due to inadequate lithium
dosage
Di culty level: Medium
9. A 57-year-old wom an com plained to her physician of trem or,
polyuria, m ental confusion, and speech disturbances. The
wom an had a diagnosis of bipolar disorder and had been
receiving lithium for 7 m onths. Tw o weeks ago, she w as
found to have successive high blood pressure readings, and
her physician started an antihypertensive treatm ent w ith
Questions: III-10 Drugs for Bipolar Disorders 117
hydrochlorothiazide and losartan. Which of the follow ing
was m ost likely the reason for the adverse e ects reported
by the patient?
A. Thiazide-induced dilutional hypernatrem ia
B. Decreased renal elim ination of lithium
C. Decreased hepatic m etabolism of lithium
D. Thiazide-induced hypokalem ia
E. Losartan-induced hyperkalem ia
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